Description

2,2-Difluoroputrescine is a specialized fluorinated derivative of the diamine putrescine, characterized by the introduction of two fluorine atoms at the alpha position. This structural modification imparts unique chemical and metabolic stability, making it a valuable intermediate for advanced synthesis. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and material science. The compound is supplied to meet the stringent requirements of modern chemical development and production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Research: Serves as a precursor for developing new fluorinated pesticides and herbicides, leveraging fluorine's ability to enhance bioavailability and environmental persistence.
• Bioconjugation & Probe Synthesis: Used in chemical biology for labeling and cross-linking applications due to its diamine functionality, which can be selectively modified.
• Polymer Chemistry: Acts as a monomer or chain extender in the production of specialty polyamides and polyurethanes with enhanced chemical resistance.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel chelating ligands for catalytic systems.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to polyamine metabolism and function.

Basic Information

Product Name	2,2-Difluoroputrescine
CAS No.	113741-09-6
Molecular Formula	C4H10F2N2
Molecular Weight	124.13 g/mol
Synonyms	1,4-Diamino-2,2-difluorobutane; 2,2-Difluoro-1,4-butanediamine; 2,2-Difluorobutane-1,4-diamine; α,α-Difluoroputrescine; DFPA; 2,2-Difluorotetramethylenediamine
EINECS	Contact for details

Quality Control

Our 2,2-Difluoroputrescine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and identity confirmation, to ensure it meets the high standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.