Description

H-Gly-Amc Hbr is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise molecular control in the development of active pharmaceutical ingredients (APIs) and complex biomolecules. It is primarily utilized by the pharmaceutical, biotechnology, and advanced life science research sectors for applications ranging from drug discovery to the production of therapeutic peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected glycine derivative for the sequential assembly of peptide chains.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel peptide-based drug candidates and APIs.
• Bioconjugation & Linker Chemistry: Used in the design and synthesis of peptide-drug conjugates (PDCs) and other targeted biopharmaceuticals.
• Research & Development: An important reagent in academic and industrial R&D for studying peptide structure-activity relationships (SAR).
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new bioactive peptides.
• Custom Peptide Production: A fundamental component for CROs and CDMOs specializing in the manufacture of custom peptides for clients.

Basic Information

Product Name	H-Gly-Amc Hbr
CAS No.	113728-13-5
Molecular Formula	C9H9BrN2O2
Molecular Weight	257.09 g/mol
Synonyms	H-Gly-AMC HBr; Glycine-7-amido-4-methylcoumarin Hydrobromide; H-Gly-AMC·HBr; Gly-AMC HBr; 7-[(2-Aminoacetyl)amino]-4-methyl-2H-1-benzopyran-2-one hydrobromide; Glycine AMC HBr; Boc-Gly-AMC HBr precursor; Peptide synthesis building block Gly-AMC
EINECS	Contact for details

Quality Control

Our H-Gly-Amc Hbr is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive applications like pharmaceutical synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including research and GMP grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.