Description

Technetium Sestamibi is a radiopharmaceutical complex used as a diagnostic imaging agent. This compound is critical for non-invasive cardiac and oncological imaging, enabling healthcare professionals to assess myocardial perfusion and locate certain tumors. It is primarily utilized by radiopharmacies, nuclear medicine departments, and research institutions involved in diagnostic procedures. The product is supplied as a sterile, non-pyrogenic lyophilized powder for reconstitution.

Application

• Myocardial Perfusion Imaging (MPI): The primary application for detecting coronary artery disease and assessing heart muscle blood flow.
• Breast Tumor Localization: Used in scintimammography to help locate and evaluate breast lesions, particularly in patients with dense breast tissue.
• Parathyroid Adenoma Localization: A key agent in pre-operative imaging to identify hyperfunctioning parathyroid glands.
• Oncologic Imaging: Employed in the detection and evaluation of certain cancers, including lung tumors and multi-drug resistance phenotypes.
• Radiopharmaceutical Kit Formulation: Serves as the active pharmaceutical ingredient (API) in the preparation of commercial diagnostic kits.
• Clinical Research: Used in research studies investigating new diagnostic applications for cardiac and oncologic conditions.

Basic Information

Product Name	Technetium Sestamibi
CAS No.	113720-90-4
Molecular Formula	C36H66N6O6Tc
Molecular Weight	777.89 g/mol (for base ligand, excluding 99mTc)
Synonyms	Technetium Tc 99m Sestamibi; Cardiolite; MIBI; [99mTc]Tc-Sestamibi; 99mTc-MIBI; Hexakis(2-methoxyisobutylisonitrile)technetium(I); Methoxy Isobutyl Isonitrile Technetium Complex
EINECS	Contact for details

Quality Control

Our Technetium Sestamibi is manufactured under strict quality systems. Each batch is tested to ensure it meets stringent specifications for radiopharmaceutical active ingredients, including purity, sterility, and apyrogenicity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for all release tests. Production adheres to current Good Manufacturing Practice (cGMP) guidelines.

Storage

Preserve in the original, tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	NLT 98.0%
Related Substances (HPLC)	Total impurities NMT 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	NMT 2.0%
Bacterial Endotoxins	< 1.0 EU/mg
Sterility	Sterile (per USP <71>)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.