Description

Papaverine-D3 is a deuterium-labeled isotopologue of the well-known vasodilator, papaverine, specifically designed for use as an internal standard in analytical chemistry. This high-purity compound is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in pharmacokinetic and metabolic studies. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, forensic, and clinical diagnostics industries who require precise measurement of papaverine levels in complex biological matrices.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of papaverine in biological samples (plasma, serum, urine).
• Metabolic pathway tracing and drug metabolism studies (DMPK) in pharmaceutical R&D.
• Forensic analysis and toxicology screening for papaverine and related compounds.
• Quality control and method validation in pharmaceutical manufacturing processes.
• Biomedical research investigating the mechanisms of vasodilation and smooth muscle relaxation.
• Calibration standard for high-precision analytical instrumentation.

Basic Information

Product Name	Papaverine-D3
CAS No.	113718-66-4
Molecular Formula	C₂₀H₂₁D₃NO₄
Molecular Weight	342.42 g/mol
Synonyms	6,7-Dimethoxy-1-veratrylisoquinoline-D3; Papaverine (methyl-D3); 1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline-D3; Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-, (methyl-D3); Deuterated Papaverine; Papaverine-d3; [2H3]-Papaverine
EINECS	Contact for details

Quality Control

Our Papaverine-D3 is manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical stability. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98% D), chemical purity (by HPLC), and confirmation of structure. We adhere to relevant industry standards for reference materials to guarantee reliable and reproducible performance in your sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98 atom % D
Chemical Purity	≥95%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.