Description

n-Methoxy-n-Methylnaphthalene-2-Carboxamide is a specialized organic compound belonging to the class of Weinreb amides, which are pivotal synthetic intermediates in modern organic chemistry. Its primary value lies in its unique reactivity as a stable acyl anion equivalent, enabling controlled and high-yielding ketone synthesis under mild conditions. This makes it an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for constructing complex naphthalene-based molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing naphthalene or polyaromatic scaffolds for therapeutic agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the naphthalene moiety imparts specific biological activity.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and fluorescent dyes due to its conjugated aromatic structure.
• Academic & R&D Laboratories: Employed in methodological development and complex molecule synthesis, leveraging its Weinreb amide functionality for precise carbonyl group transformations.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, fragrances, and other high-value organic compounds.

Basic Information

Product Name	n-Methoxy-n-Methylnaphthalene-2-Carboxamide
CAS No.	113443-62-2
Molecular Formula	C₁₄H₁₅NO₂
Molecular Weight	229.27 g/mol
Synonyms	2-Naphthoic Acid N-Methoxy-N-Methylamide; N-Methoxy-N-Methyl-2-naphthamide; N-Methoxy-N-methyl-2-naphthalenecarboxamide; N,2-Dimethoxy-N-methyl-2-naphthamide; Weinreb Amide of 2-Naphthoic Acid; N-Methoxy-N-methylnaphthalene-2-carboxamide; N-Methyl-N-methoxy-2-naphthamide; 2-(N-Methoxy-N-methylcarbamoyl)naphthalene
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methylnaphthalene-2-Carboxamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards expected in pharmaceutical and fine chemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.