Description

1H-Pyrazol-1-Ylacetonitrile is a versatile pyrazole-based nitrile building block, essential for advanced organic synthesis. This high-purity intermediate is valued for its reactivity, enabling the construction of complex heterocyclic frameworks and functional molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrazole moiety's bioactivity.
• Ligand and Catalyst Development: Serves as a functional handle for constructing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials and advanced polymers with tailored properties.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1H-Pyrazol-1-Ylacetonitrile
CAS No.	113336-22-4
Molecular Formula	C5H5N3
Molecular Weight	107.11 g/mol
Synonyms	1H-Pyrazol-1-ylacetonitrile; (1H-Pyrazol-1-yl)acetonitrile; 1-Pyrazolylacetonitrile; Pyrazole-1-acetonitrile; 1-Cyanomethylpyrazole; (Pyrazol-1-yl)acetonitrile; 1H-Pyrazol-1-yl-acetonitrile; 113336-22-4
EINECS	Contact for details

Quality Control

Our 1H-Pyrazol-1-Ylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider maintaining the material under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.