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2-Amino-2-(Thiophen-3-Yl)Acetonitrile CAS NO 113100-57-5


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CAS No.:113100-57-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Amino-2-(Thiophen-3-Yl)Acetonitrile is a versatile nitrile derivative and a valuable bifunctional building block in advanced organic synthesis. Its structure, featuring both an amino group and a nitrile adjacent to a thiophene ring, makes it a critical precursor for constructing complex heterocyclic systems and pharmacologically active molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides that incorporate thiophene motifs for enhanced bioactivity.
  • Material Science Precursor: Serves as a building block for organic semiconductors, conductive polymers, and nonlinear optical (NLO) materials due to the electron-rich thiophene unit.
  • Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands and organocatalysts for asymmetric synthesis.
  • Chemical Research (R&D): A fundamental reagent in academic and industrial laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Item Details
Product Name 2-Amino-2-(Thiophen-3-Yl)Acetonitrile
CAS No. 113100-57-5
Molecular Formula C7H6N2S
Molecular Weight 150.20 g/mol
Synonyms 2-Amino-2-(3-thienyl)acetonitrile; (Aminothiophen-3-yl)acetonitrile; 3-Thiopheneacetonitrile, α-amino-; α-Amino-3-thiopheneacetonitrile; 2-Amino-2-(thiophen-3-yl)ethanenitrile; 113100-57-5; (3-Thienyl)glycinonitrile
EINECS Contact for details

Quality Control

Every batch of 2-Amino-2-(Thiophen-3-Yl)Acetonitrile is manufactured under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, GC, and NMR. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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