Description

Acetonitrile, 2-[4-(Chloromethyl)Phenoxy]- is a versatile bifunctional organic intermediate featuring both an acetonitrile and a reactive chloromethyl group. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional polymers and advanced organic materials with specific electronic or structural properties.
• Cross-Coupling Reactions: The chloromethyl group facilitates further functionalization via palladium-catalyzed or other metal-mediated coupling reactions.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Acetonitrile, 2-[4-(Chloromethyl)Phenoxy]-
CAS No.	112772-83-5
Molecular Formula	C10H10ClNO
Molecular Weight	195.65 g/mol
Synonyms	2-[4-(Chloromethyl)phenoxy]acetonitrile; 4-(Chloromethyl)phenoxyacetonitrile; (4-Chloromethylphenoxy)acetonitrile; 2-(4-Chloromethylphenoxy)acetonitrile; p-(Chloromethyl)phenoxyacetonitrile; Acetonitrile, (p-(chloromethyl)phenoxy)-; Glycolonitrile, 2-(p-(chloromethyl)phenoxy)-; A key phenoxy acetonitrile derivative.
EINECS	Contact for details

Quality Control

Our Acetonitrile, 2-[4-(Chloromethyl)Phenoxy]- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.