Description

7-(2-(2-Aminothiazolyl)-2-Methoxyiminoacetamido)-3-(Imidazo(1,2-A)Pyridinium-1-Yl)Methyl-3-Cephem-4-Carboxylate is a key advanced pharmaceutical intermediate in the synthesis of modern cephalosporin antibiotics. This compound is critical for developing potent antibacterial agents with enhanced stability against β-lactamase enzymes. It is primarily required by pharmaceutical R&D laboratories and manufacturers specializing in the production of broad-spectrum, injectable antibiotics.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of fourth-generation cephalosporin antibiotics.
• Antibacterial Drug Development: Serves as a core building block for new chemical entities targeting resistant bacterial strains.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the critical chemical steps to form the final active drug substance.
• Research & Development: Essential for academic and industrial research into novel β-lactam structures and mechanisms.
• Process Chemistry & Scale-Up: Employed in optimizing manufacturing routes for cephalosporin-based drugs.

Basic Information

Product Name	7-(2-(2-Aminothiazolyl)-2-Methoxyiminoacetamido)-3-(Imidazo(1,2-A)Pyridinium-1-Yl)Methyl-3-Cephem-4-Carboxylate
CAS No.	112601-22-6
Molecular Formula	C20H19N7O5S2
Molecular Weight	501.54 g/mol
Synonyms	Cefepime Intermediate; Cefepime Impurity; (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methylimidazo[5,1-b]thiazol-2-ium-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefepime Side Chain Derivative; 7-ACA Derivative; Aminothiazolyl Methoxyimino Cephem; Antibiotic Intermediate 112601-22-6
EINECS	Contact for details

Quality Control

Our 7-(2-(2-Aminothiazolyl)-2-Methoxyiminoacetamido)-3-(Imidazo(1,2-A)Pyridinium-1-Yl)Methyl-3-Cephem-4-Carboxylate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.