Description

Hemoglobin J Auckland is a specific variant of hemoglobin, a critical oxygen-transporting metalloprotein found in red blood cells. This high-purity biochemical is essential for advanced research and diagnostic applications requiring precise and consistent protein standards. It serves as a vital reference material for clinical laboratories, biopharmaceutical developers, and academic researchers studying hemoglobinopathies, oxygen transport mechanisms, and related hematological conditions.

Application

• Clinical Diagnostics & Calibration: Used as a certified reference standard in clinical analyzers for the accurate quantification and identification of hemoglobin variants.
• Biomedical Research: Fundamental for in-vitro studies on hemoglobin structure-function relationships, oxygen affinity, and the pathophysiology of hemoglobin disorders like Hemoglobin J disease.
• Biopharmaceutical Development: Acts as a model protein in the development of blood substitutes, oxygen carriers, and novel therapeutic agents targeting hemoglobin.
• Hematology Standards: Provides a critical component for preparing quality control materials and proficiency testing samples in hematology laboratories.
• Educational & Training Kits: Incorporated into educational kits for medical and life sciences training to demonstrate protein electrophoresis and genetic disease principles.

Basic Information

Product Name	Hemoglobin J Auckland
CAS No.	112444-78-7
Molecular Formula	C2952H4664N812O840S16Fe4
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb J-Auckland; Hemoglobin variant J Auckland; α-2 globin chain variant; HBA2 p.Ala129Asp; Hemoglobin alpha chain mutant J-Auckland; Deoxyhemoglobin J Auckland; Oxyhemoglobin J Auckland; Methemoglobin J Auckland
EINECS	Contact for details

Quality Control

Our Hemoglobin J Auckland is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical applications. Each lot is characterized for identity, purity, and functional integrity using advanced analytical techniques including HPLC, electrophoresis, and spectrophotometry. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -80°C to prevent repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use in a low-humidity environment.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/Electrophoresis)	Conforms to standard
Purity (HPLC)	≥ 95%
Assay (Spectrophotometric)	≥ 90% of theoretical
Water Content (Karl Fischer)	≤ 5.0 %
Biological Activity (Oxygen Binding)	Contact for details
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.