Description

N(6)-4-Azidosalicylylkallidin is a specialized, photoactivatable derivative of the peptide kallidin, designed for advanced biochemical research. This compound is critical for researchers investigating bradykinin receptor (B1/B2) interactions and signaling pathways through covalent cross-linking techniques. It is primarily utilized by pharmaceutical R&D teams and academic laboratories focused on cardiovascular biology, inflammation, and neuropharmacology for precise target identification and mapping studies.

Application

• Photoaffinity Labeling: Acts as a covalent probe for the identification and characterization of bradykinin B1 and B2 receptor binding sites.
• Biochemical Research: Used in studies of kinin-mediated physiological processes, including vasodilation, pain signaling, and inflammatory responses.
• Drug Discovery: Serves as a key tool compound in high-throughput screening assays and structure-activity relationship (SAR) studies for novel receptor antagonists.
• Proteomics & Target Identification: Enables the isolation and analysis of receptor complexes and interacting proteins through UV-induced cross-linking.
• Molecular Imaging Probe Development: A precursor for creating labeled analogs for advanced imaging techniques in pharmacological research.

Basic Information

Product Name	N(6)-4-Azidosalicylylkallidin
CAS No.	112430-78-1
Molecular Formula	C58H85N15O12
Molecular Weight	1168.4 g/mol
Synonyms	4-Azidosalicylamidokallidin; N6-(4-Azidosalicyl)kallidin; Kallidin, N6-(4-azidosalicyl)-; ASK; Photoactivatable Kallidin; Bradykinin B2 Receptor Photoaffinity Probe; Lys0-[Nε-(4-azidosalicyl)]-bradykinin
EINECS	Contact for details

Quality Control

Every batch of N(6)-4-Azidosalicylylkallidin is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency for research reproducibility. Our products undergo rigorous quality testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake and decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.