Description

Somatotropin Releasing Hormone-(1-29), 1-His-2-Ala-27-Nle- is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). This compound is engineered for enhanced stability and biological activity, making it a critical research tool and a key intermediate in advanced pharmaceutical development. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in endocrinology research and peptide-based therapeutic discovery.

Application

• Endocrinology Research: Fundamental studies on growth hormone (GH) secretion mechanisms and pituitary function.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of novel GHRH analogs and growth hormone secretagogues.
• Biochemical Assays: Used in receptor binding studies, signal transduction pathway analysis, and in vitro bioactivity testing.
• Veterinary Science: Investigation of growth promotion and metabolic effects in animal models.
• Diagnostic Tool Development: Potential use in calibrating assays for growth hormone dynamics.

Basic Information

Product Name	Somatotropin Releasing Hormone-(1-29), 1-His-2-Ala-27-Nle-
CAS No.	112372-78-8
Molecular Formula	C149H246N44O42
Molecular Weight	~3359.9 g/mol
Synonyms	GHRH (1-29) amide, human; [His1, Ala2, Nle27]-hGHRH(1-29)-NH2; Somatoliberin (1-29) amide, human; Growth Hormone-Releasing Factor (1-29), human; hGHRH(1-29)NH2 analog; GRF (1-29); Tesamorelin precursor; Geref precursor
EINECS	Contact for details

Quality Control

Our Somatotropin Releasing Hormone-(1-29), 1-His-2-Ala-27-Nle- is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide comprehensive Certificates of Analysis (COA) detailing all specifications to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.