Description

Ecopipam is a highly selective dopamine D1 receptor antagonist, representing a significant compound in neuropharmacological research and development. Its specific mechanism of action makes it a valuable tool for investigating and targeting pathways related to reward, motivation, and certain behavioral disorders. This compound is primarily utilized by pharmaceutical R&D teams, academic research institutions, and clinical trial organizations. It serves as a critical active pharmaceutical ingredient (API) and reference standard for advanced therapeutic development.

Application

• Pharmaceutical R&D: Core active pharmaceutical ingredient (API) for developing novel therapeutics targeting dopamine D1 receptors.
• Clinical Research: Investigational agent in clinical trials for conditions such as substance use disorders, Tourette syndrome, and obesity.
• Neuroscience Research: Critical pharmacological tool for in vitro and in vivo studies to elucidate the role of dopamine D1 receptors in brain function and behavior.
• Reference Standard: High-purity material used for analytical method development, validation, and quality control in regulatory submissions.
• Preclinical Development: Used in pharmacokinetic, pharmacodynamic, and toxicology studies to support Investigational New Drug (IND) applications.

Basic Information

Product Name	Ecopipam
CAS No.	112107-92-3
Molecular Formula	C19H19Cl2NO4
Molecular Weight	396.27 g/mol
Synonyms	(+)-Ecopipam; (6aS,10bR)-3,4,6a,7,8,9,10,10b-Octahydro-1H-benzofuro[2,3-c]pyrido[3,2,1-jk]carbazole-1,9(2H)-dione; BMS-181,101; SCH-39166; R-(+)-SCH-39166; Dopamine D1 receptor antagonist SCH-39166
EINECS	Contact for details

Quality Control

Our Ecopipam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods, purity assay by HPLC, and stringent control of related substances and residual solvents. We provide full traceability and support regulatory filings with comprehensive documentation. Certificates of Analysis (COA) are available upon request, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.