Description

[[1,1'-Biphenyl]-2,2'-Diylbis(Methylene)]Bis[Diphenylphosphine] is a sophisticated, bidentate phosphine ligand widely utilized in advanced catalytic processes. This compound matters for its ability to facilitate challenging cross-coupling and hydrogenation reactions, enabling the efficient synthesis of complex organic molecules. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and high-value intermediates. Its unique steric and electronic properties make it a valuable tool for optimizing reaction selectivity and yield.

Application

• As a key ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations, for C-C and C-N bond formation.
• In asymmetric hydrogenation catalysts for the production of enantiomerically pure chiral compounds in pharmaceutical synthesis.
• For catalyst development and screening in academic and industrial research laboratories exploring new synthetic methodologies.
• As a precursor or modifying agent in the preparation of specialized metal-organic complexes and materials.
• In the synthesis of advanced organic electronic materials and functional polymers where precise molecular architecture is critical.

Basic Information

Product Name	[[1,1'-Biphenyl]-2,2'-Diylbis(Methylene)]Bis[Diphenylphosphine]
CAS No.	111982-81-1
Molecular Formula	C38H32P2
Molecular Weight	550.61 g/mol
Synonyms	2,2'-Bis(diphenylphosphinomethyl)-1,1'-biphenyl; BIPHEP; 2,2'-Bis(diphenylphosphanylmethyl)-1,1'-biphenyl; Biphenyl-2,2'-diylbis(methylene) bis(diphenylphosphine); (2,2'-Biphenyldiyl)bis(methylene)bis(diphenylphosphine); BIPHEP Ligand; 1,1'-Biphenyl-2,2'-diylbis(methylene) bis(diphenylphosphane); NSC 682520
EINECS	Contact for details

Quality Control

Our [[1,1'-Biphenyl]-2,2'-Diylbis(Methylene)]Bis[Diphenylphosphine] is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and process development in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.