Description

Zervamicin A1-16 is a specialized peptide antibiotic belonging to the peptaibol class, characterized by its unique sequence of amino acids including the non-proteinogenic amino acid isovaline. This compound is valued for its potent membrane-disrupting activity, making it a critical tool for microbiological research and development. It is primarily utilized by researchers in the pharmaceutical and biotechnology sectors for studying ion channel formation, antimicrobial mechanisms, and developing novel therapeutic agents.

Application

• Antimicrobial Research: Used as a reference standard and active agent in studies targeting Gram-positive bacteria and fungi.
• Membrane Biophysics: Employed to investigate ion channel formation and pore dynamics in lipid bilayers and cell membranes.
• Pharmaceutical Development: Serves as a lead compound or model for the design of new peptide-based antibiotics and antifungal drugs.
• Biochemical Assays: Utilized in bioassays to screen for antimicrobial activity and evaluate resistance mechanisms.
• Academic & Industrial R&D: A key reagent for universities and contract research organizations (CROs) exploring novel bioactive peptides.

Basic Information

Product Name	Zervamicin A1-16
CAS No.	111908-11-3
Molecular Formula	C84H138N20O21
Molecular Weight	1764.1 g/mol
Synonyms	Zervamicin I; Zervamicin IA; Antibiotic IA 887; Peptaibol IA 887; L-Leucyl-L-alanyl-L-α-aminoisobutyryl-L-α-aminoisobutyryl-L-alanyl-L-α-aminoisobutyryl-L-α-aminoisobutyryl-L-glutaminyl-L-α-aminoisobutyryl-L-α-aminoisobutyryl-L-leucyl-L-α-aminoisobutyryl-L-prolyl-L-leucyl-L-α-aminoisobutyryl-L-isovalineol
EINECS	Contact for details

Quality Control

Our Zervamicin A1-16 is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material suitable for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.