Description

Cefprozil (E)-Isomer (50 Mg) is a high-purity, stereochemically defined isomer of the broad-spectrum cephalosporin antibiotic, Cefprozil. This specific isomer is critical for pharmaceutical research and development, particularly in studies of structure-activity relationships, metabolic pathways, and analytical method development. It is an essential reference standard and intermediate for researchers and manufacturers in the pharmaceutical and fine chemical industries focused on antibiotic development and quality control.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of Cefprozil in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Research: Serves as a key intermediate or starting material in the research and synthesis of novel cephalosporin derivatives.
• Analytical Method Development: Essential for developing and validating chromatographic methods (HPLC, LC-MS) to separate and quantify the (E)-isomer from other stereoisomers or impurities.
• Metabolic and Pharmacokinetic Studies: Employed in research to understand the absorption, distribution, metabolism, and excretion (ADME) profile of the specific isomer.
• Regulatory Compliance and Documentation: Supports regulatory filings by providing definitive characterization data for drug substance specifications.

Basic Information

Product Name	Cefprozil (E)-Isomer (50 Mg)
CAS No.	111900-24-4
Molecular Formula	C18H19N3O5S
Molecular Weight	389.43 g/mol
Synonyms	(6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(E)-1-propen-1-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (E)-Cefprozil; Cefprozil Isomer E; Cefzil Isomer; BMY-28100 Isomer; (±)-Cis/Trans-Cefprozil (E-isomer); Antibiotic BMY 28100 (E-isomer)
EINECS	Contact for details

Quality Control

Our Cefprozil (E)-Isomer is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.