Description

H-Gly-Arg-Gly-Asp-D-Ser-Pro-OH is a synthetic peptide sequence derived from the cell adhesion protein fibronectin. This compound is a critical research-grade biochemical tool, specifically designed to mimic the natural RGD (Arg-Gly-Asp) motif that mediates cellular interactions with the extracellular matrix. It is essential for scientists and manufacturers in the fields of biomaterials development, tissue engineering, and cell biology research, where precise control over cell attachment and behavior is required.

Application

• Biomaterial and Implant Coating: Used to functionalize surfaces of medical devices, scaffolds, and implants to promote specific cell adhesion and integration.
• Cell Culture Research: Serves as a key component in studies investigating integrin-mediated cell signaling, migration, and proliferation.
• Tissue Engineering: Incorporated into hydrogels and 3D matrices to create bioactive environments that guide tissue formation and regeneration.
• Diagnostic Assay Development: Employed in the development of assays for screening compounds that modulate cell adhesion pathways.
• Drug Delivery Systems: Utilized to enhance the targeting and biocompatibility of nanoparticle and polymeric drug carriers.
• Basic Biochemical Research: Acts as a standard or inhibitor in studies focused on protein-protein interactions involving integrin receptors.

Basic Information

Product Name	H-Gly-Arg-Gly-Asp-D-Ser-Pro-OH
CAS No.	111844-24-7
Molecular Formula	C23H38N10O10
Molecular Weight	614.61 g/mol
Synonyms	GRGDS Peptide; GRGDS-OH; H-Gly-Arg-Gly-Asp-Ser-Pro-OH (D-Ser isomer); Fibronectin Fragment (GRGDS); Arg-Gly-Asp-Ser-Pro Peptide; Cell Adhesion Peptide GRGDS; GRGDS; Cyclo(-GRGDSP)
EINECS	Contact for details

Quality Control

Our H-Gly-Arg-Gly-Asp-D-Ser-Pro-OH is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent analytical standards typical for research biochemicals, ensuring reliable performance in your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.