Description

4-n-Hydroxy-2,4-Diaminobutyric Acid is a specialized, non-proteinogenic amino acid derivative featuring both hydroxyl and diamine functional groups on its butyric acid backbone. This unique bifunctional structure makes it a valuable chiral building block and intermediate for synthesizing complex bioactive molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for applications in drug discovery and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide mimetics, enzyme inhibitors, and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a precursor or standard in metabolic pathway studies and proteomics research.
• Ligand Synthesis: Serves as a building block for creating chelating agents and complexing ligands in coordination chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials.
• Peptide Modification: Utilized to introduce hydroxyl and additional amino functionalities into synthetic peptides to alter their properties.

Basic Information

Product Name	4-n-Hydroxy-2,4-Diaminobutyric Acid
CAS No.	111821-59-1
Molecular Formula	C₄H₁₀N₂O₃
Molecular Weight	134.13 g/mol
Synonyms	2,4-Diamino-4-hydroxybutyric acid; 4-Amino-2-amino-4-hydroxybutanoic acid; 4-Hydroxy-2,4-diaminobutanoic acid; H-Dab(4-OH)-OH; (2R,4S)-2,4-Diamino-4-hydroxybutyric acid (for stereoisomer); D-erythro-2,4-Diamino-4-hydroxybutyric acid; L-threo-2,4-Diamino-4-hydroxybutyric acid; 4-OH-Dab
EINECS	Contact for details

Quality Control

Our 4-n-Hydroxy-2,4-Diaminobutyric Acid is produced under a strict quality management system. Each batch is analyzed to ensure high purity and consistency, with testing typically including identification, assay, chiral purity, and control of related substances. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specified isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.