Description

n-tert-Butyl-4-(Chloromethyl)Benzamide is a high-purity organic intermediate featuring a reactive chloromethyl group and a bulky tert-butyl amide moiety. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those requiring a sterically hindered benzamide scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: The reactive chloromethyl group allows for incorporation into polymer chains to impart specific chemical functionalities.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	n-tert-Butyl-4-(Chloromethyl)Benzamide
CAS No.	111818-35-0
Molecular Formula	C12H16ClNO
Molecular Weight	225.72 g/mol
Synonyms	4-(Chloromethyl)-N-(tert-butyl)benzamide; N-(tert-Butyl)-4-(chloromethyl)benzamide; p-(Chloromethyl)-N-tert-butylbenzamide; Benzamide, N-(1,1-dimethylethyl)-4-(chloromethyl)-; 1-tert-Butylcarbamoyl-4-chloromethyl-benzene; 4-(Chloromethyl)-N-(1,1-dimethylethyl)benzamide
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-4-(Chloromethyl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.