Description

Cefetamet Pivoxil Hydrochloride is a third-generation cephalosporin antibiotic prodrug, specifically designed for enhanced oral bioavailability. Its primary value lies in its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria, making it a critical intermediate in pharmaceutical manufacturing. This compound is essential for producers of finished dosage forms, such as tablets and capsules, targeting the treatment of respiratory, urinary tract, and other bacterial infections.

Application

• Primary active pharmaceutical ingredient (API) in the synthesis of oral antibiotic formulations.
• Key intermediate for the production of finished dosage forms like tablets and capsules.
• Used in pharmaceutical research and development for new antibacterial therapies.
• Critical raw material for generic drug manufacturers producing cephalosporin-based antibiotics.
• Employed in clinical trial material (CTM) production for new drug applications.
• Utilized in the development of combination therapies for enhanced efficacy.

Basic Information

Product Name	Cefetamet Pivoxil Hydrochloride
CAS No.	111696-23-2
Molecular Formula	C20H25N5O7S2 · HCl
Molecular Weight	564.04 g/mol
Synonyms	Cefetamet Pivoxil HCl; (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid pivaloyloxymethyl ester hydrochloride; Ro 15-8075; CI-1015; Cefetamet pivoxil monohydrochloride
EINECS	Contact for details

Quality Control

Our Cefetamet Pivoxil Hydrochloride is manufactured under strict quality systems to ensure it meets the rigorous standards required for pharmaceutical intermediates. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure compliance with in-house specifications aligned with ICH guidelines. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.