Description

Naltrindol is a highly selective and potent delta opioid receptor (DOP) antagonist. This compound is a critical research tool for investigating the physiological and pharmacological roles of the delta opioid receptor system in the central nervous system. It is primarily utilized by pharmaceutical researchers, neuroscientists, and academic institutions engaged in neuropharmacology, pain management research, and the development of novel therapeutic agents targeting opioid pathways.

Application

• Neuroscience Research: A fundamental tool for studying the function and distribution of delta opioid receptors in the brain and spinal cord.
• Pharmacological Profiling: Used in in vitro and in vivo assays to characterize new chemical entities targeting opioid receptors.
• Pain Mechanism Studies: Employed to dissect the specific contribution of delta receptors to analgesia, tolerance, and dependence.
• Drug Discovery & Development: Serves as a reference standard and pharmacological probe in the R&D pipeline for novel analgesics and neuropsychiatric drugs.
• Academic & Clinical Research: Supports investigations into the role of delta receptors in mood, addiction, and other neurological disorders.

Basic Information

Product Name	Naltrindol
CAS No.	111555-53-4
Molecular Formula	C26H27NO4
Molecular Weight	417.50 g/mol
Synonyms	Naltrindole; 17-Cyclopropylmethyl-6,7-dehydro-4,5α-epoxy-3,14-dihydroxy-6,7,2',3'-indolomorphinan; NTB; NTI; Naltrindole Hydrochloride (salt form); δ-Opioid Receptor Antagonist
EINECS	Contact for details

Quality Control

Our Naltrindol is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.