Description

2,4-Dinitrophenyl-2-Fluoro-2-Deoxy-β-D-Glucopyranoside is a specialized fluorinated glycoside derivative that serves as a critical biochemical tool. This compound is valued for its role as a chromogenic substrate in enzymatic assays, particularly for detecting and quantifying the activity of glycoside hydrolases like β-glucosidase. It is essential for researchers and manufacturers in the fields of biochemistry, enzymology, and pharmaceutical development who require precise, high-purity substrates for diagnostic and research applications.

Application

• Enzymatic Substrate for β-Glucosidase: Primary use as a chromogenic substrate in biochemical assays to measure enzyme kinetics and activity.
• Diagnostic Reagent Development: Key component in the formulation of diagnostic kits for genetic disorders like Gaucher's disease, where glucocerebrosidase activity is measured.
• Biochemical Research: Used in laboratory studies to investigate enzyme inhibition, mechanism of action, and substrate specificity of various glycosidases.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify potential therapeutic inhibitors for enzyme-related diseases.
• Quality Control in Biomanufacturing: Acts as a standard reagent to ensure the consistency and potency of enzyme-based biopharmaceutical products.

Basic Information

Product Name	2,4-Dinitrophenyl-2-Fluoro-2-Deoxy-β-D-Glucopyranoside
CAS No.	111495-86-4
Molecular Formula	C₁₂H₁₃FN₂O₉
Molecular Weight	348.24 g/mol
Synonyms	2,4-Dinitrophenyl 2-Fluoro-2-deoxy-β-D-glucopyranoside; 2-Fluoro-2-deoxy-β-D-glucopyranoside 2,4-dinitrophenyl; DNP-F-Glc; 2,4-DNP-2F-β-Glc; β-D-Glucopyranoside, 2,4-dinitrophenyl 2-fluoro-2-deoxy-; 2-Fluoro-2-deoxy-D-glucopyranoside 2,4-dinitrophenyl ether; Fluorodeoxyglucoside DNP derivative
EINECS	Contact for details

Quality Control

Our 2,4-Dinitrophenyl-2-Fluoro-2-Deoxy-β-D-Glucopyranoside is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for fine chemicals and can provide material suitable for use under GMP guidelines for critical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.