Description

n-(Ethoxycarbonyl)-DL-Valine is a protected amino acid derivative, specifically the ethoxycarbonyl (N-Cbz) derivative of racemic valine. This compound serves as a crucial chiral building block and intermediate in sophisticated organic synthesis, offering controlled reactivity for the selective formation of peptide bonds and other complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs, prodrugs, and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected valine residue, where the ethoxycarbonyl group acts as a temporary amine protector.
• Agrochemical Research: Serves as a building block for synthesizing novel herbicides, fungicides, and plant growth regulators with specific chiral configurations.
• Bioconjugation & Linker Chemistry: Employed in the design and synthesis of chemical linkers and conjugates for biopharmaceuticals and diagnostic agents.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and asymmetric synthesis studies.
• Specialty Chemical Production: Used in the manufacture of chiral catalysts, ligands, and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	n-(Ethoxycarbonyl)-DL-Valine
CAS No.	111421-95-5
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	DL-Valine, N-[(ethoxycarbonyl)]-; N-Carbobenzoxy-DL-valine; N-Cbz-DL-valine; Carbobenzyloxy-DL-valine; (RS)-2-[(Ethoxycarbonyl)amino]-3-methylbutanoic acid; Z-DL-Val-OH; DL-Valine, N-carboxy-, ethyl ester; Ethyl N-(DL-valyl)carbamate
EINECS	Contact for details

Quality Control

Our n-(Ethoxycarbonyl)-DL-Valine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets high-grade specifications for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-Racemate
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.