Description

Propanamide, n-[[(2-Mercaptoethyl)Amino]Carbonyl]- is a specialized organic compound featuring both amide and thiol functional groups, making it a valuable intermediate in advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring a precise building block to introduce specific reactivity or modify material properties. It is primarily utilized in the development of pharmaceuticals, agrochemicals, and specialty polymers where controlled molecular architecture is essential.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting specific enzyme inhibition or designed for prodrug strategies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that require a thiol-containing moiety.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce thiol groups into polymer backbones, enhancing properties like adhesion, self-healing capability, or metal-binding characteristics.
• Bioconjugation Chemistry: Employed in the development of linkers for attaching drugs, dyes, or other molecules to proteins, antibodies, or nanoparticles in biotech applications.
• Chemical Research & Development: A valuable reagent in organic synthesis for constructing complex molecules, studying reaction mechanisms, or developing new catalytic systems.
• Material Science: Used in the surface functionalization of metals or inorganic materials to improve corrosion resistance or create specific surface chemistries.

Basic Information

Product Name	Propanamide, n-[[(2-Mercaptoethyl)Amino]Carbonyl]-
CAS No.	111278-19-4
Molecular Formula	C6H12N2O2S
Molecular Weight	176.24 g/mol
Synonyms	N-[(2-Mercaptoethyl)carbamoyl]propanamide; 2-[(2-Mercaptoethyl)carbamoyl]acetamide; 3-Oxo-N-(2-sulfanylethyl)propanamide; N-(2-Sulfanylethyl)malonamic acid amide; Propanamide, N-[(2-mercaptoethyl)carbamoyl]-; 111278-19-4; N-(2-Mercaptoethyl)malonamide
EINECS	Contact for details

Quality Control

Our Propanamide, n-[[(2-Mercaptoethyl)Amino]Carbonyl]- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent oxidation of the thiol group.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.