Description

H-β-Ala-Pna Hbr is a specialized peptide derivative, a key building block in advanced organic synthesis and pharmaceutical research. This compound is valued for its role as a protected amino acid intermediate, enabling the precise construction of complex peptide sequences. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Research: Used in proteomics and enzymology studies as a substrate or inhibitor analog for investigating enzyme mechanisms.
• Peptide Synthesis: Serves as a protected building block in solid-phase and solution-phase peptide synthesis (SPPS) for creating custom sequences.
• Protease Substrate: Acts as a chromogenic or fluorogenic substrate in assays for detecting and characterizing protease enzyme activity.
• Chemical Biology Probes: Employed in the development of activity-based probes (ABPs) for labeling and studying specific enzyme families in complex biological systems.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Item	Detail
Product Name	H-β-Ala-Pna Hbr
CAS No.	111196-17-9
Molecular Formula	C13H18BrN3O3
Molecular Weight	344.21 g/mol
Synonyms	H-β-Ala-pNA HBr; N-(3-Aminopropanoyl)-4-nitroaniline Hydrobromide; β-Ala-pNA HBr; H-β-Ala-p-Nitroanilide Hydrobromide; 3-[(4-Nitrophenyl)amino]-3-oxopropanoic Acid Amide Hydrobromide; Boc-β-Ala-pNA HBr (if Boc-protected precursor); β-Alanine p-nitroanilide hydrobromide
EINECS	Contact for details

Quality Control

Our H-β-Ala-Pna Hbr is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identification. Our quality commitment supports applications requiring research-grade and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.