Description

Peptide n-Fattyacylase CAS NO 111174-43-7 is a specialized enzyme catalyst designed for the selective acylation of peptide N-termini with fatty acid derivatives. This compound is critical for researchers and manufacturers seeking to modify peptide properties, such as enhancing lipophilicity, membrane permeability, and metabolic stability. It is an essential reagent for pharmaceutical R&D, particularly in the development of peptide-based therapeutics, prodrugs, and advanced biomaterials.

Application

• Pharmaceutical Synthesis: Key intermediate in the production of lipidated peptide drugs to improve bioavailability and targeting.
• Bioconjugation: Used for attaching fatty acid chains to peptides and proteins for creating novel bioconjugates and drug delivery systems.
• Proteomics Research: A tool enzyme for selective N-terminal modification in peptide mapping, sequencing, and functional studies.
• Cosmetic Peptide Actives: Modification of peptide ingredients to enhance skin penetration and stability in anti-aging and dermal formulations.
• Biomaterial Engineering: Facilitating the synthesis of peptide-amphiphiles for self-assembling nanostructures and hydrogels.
• Academic & Industrial R&D: Serves as a critical reagent for exploring structure-activity relationships (SAR) in peptide science.

Basic Information

Product Name	Peptide n-Fattyacylase
CAS No.	111174-43-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Fattyacyl peptide synthase; Peptide N-terminal acyltransferase; N-Acyl peptide synthetase; Fatty acid-peptide ligase; N-Terminal fatty acylase; CAS 111174-43-7; Lipopeptide synthase (related function); N-Acylation enzyme
EINECS	Contact for details

Quality Control

Our Peptide n-Fattyacylase is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high catalytic activity, purity, and lot-to-lot consistency. Certificates of Analysis (COA) detailing specific activity, purity by HPLC, and absence of contaminating proteases are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95%
Specific Activity	Contact for details
Protein Content (Biuret)	Contact for details
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.