Description

7-(Trifluoromethyl)Chroman-4-One is a versatile fluorinated organic intermediate characterized by its chromanone core and trifluoromethyl substituent. This structural motif is highly valued for its ability to impart desirable properties such as metabolic stability and enhanced lipophilicity to target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals and functional materials with unique optical or electronic properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial laboratories for methodological studies and as a substrate for novel fluorination or cyclization reactions.

Basic Information

Product Name	7-(Trifluoromethyl)Chroman-4-One
CAS No.	111141-02-7
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	7-(Trifluoromethyl)-4-chromanone; 7-(Trifluoromethyl)-2,3-dihydro-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 7-(trifluoromethyl)-2,3-dihydro-; 7-Trifluoromethylchroman-4-one; 7-(Trifluoromethyl)-4-chromone; Chroman-4-one, 7-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Chroman-4-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.