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(-)-Phenyl-4,6-o-(R)-Benzylidene-2,3-o-Bis-(Diphenylphosphino)-β-D-Glucopyranoside CAS NO 111137-94-1


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CAS No.:111137-94-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(-)-Phenyl-4,6-o-(R)-Benzylidene-2,3-o-Bis-(Diphenylphosphino)-β-D-Glucopyranoside is a sophisticated chiral ligand and a key intermediate in asymmetric synthesis. This compound matters for its ability to induce high enantioselectivity in catalytic reactions, which is critical for producing single-isomer pharmaceuticals and fine chemicals. It is primarily needed by research institutions and industrial chemists working in pharmaceutical development, agrochemical synthesis, and advanced material science.

Application

  • Asymmetric Hydrogenation Catalyst Ligand: For the enantioselective synthesis of chiral amino acids, pharmaceutical intermediates, and other bioactive molecules.
  • Pharmaceutical Intermediate: Used in the research and development of novel therapeutic agents requiring high stereochemical purity.
  • Chiral Auxiliary in Organic Synthesis: Facilitates the creation of complex, stereodefined molecular architectures in fine chemical production.
  • Agrochemical Synthesis: Enables the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Academic and Industrial R&D: A valuable tool for methodology development in catalysis and stereochemistry studies.
  • Material Science Research: Potential applications in the development of chiral polymers and advanced functional materials.

Basic Information

Product Name (-)-Phenyl-4,6-o-(R)-Benzylidene-2,3-o-Bis-(Diphenylphosphino)-β-D-Glucopyranoside
CAS No. 111137-94-1
Molecular Formula C49H44O6P2
Molecular Weight 790.82 g/mol
Synonyms (-)-Phenyl 4,6-O-(R)-Benzylidene-2,3-O-Bis(diphenylphosphino)-β-D-glucopyranoside; (2R,3R,4R,5R,6R)-5-[(R)-Phenyl(phenylmethoxy)methyl]-2-(diphenylphosphanyloxy)-6-(diphenylphosphanyloxymethyl)oxane-3,4-diol; Benzylidene-DIPHOS-Glucoside; β-D-Glucopyranoside, phenyl 4,6-O-[(R)-phenylmethylene]-2,3-bis-O-(diphenylphosphino)-, (-)-; Chiral DIPHOS ligand derivative; Phenyl 4,6-O-benzylidene-2,3-O-bis(diphenylphosphino)-β-D-glucopyranoside
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Enantiomeric Purity (Chiral HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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