Description

Trigramin CAS NO 111019-84-2 is a specialized synthetic peptide compound with significant biological activity. It serves as a potent and selective inhibitor of trypsin-like serine proteases, making it a critical tool for biochemical research and pharmaceutical development. This compound is essential for researchers and manufacturers in the fields of protease inhibitor development, diagnostic reagent formulation, and biochemical pathway analysis.

Application

• Biochemical Research: Used as a specific inhibitor to study the function and regulation of trypsin, thrombin, and related serine proteases in enzymatic assays.
• Pharmaceutical Development: Serves as a lead compound or reference standard in the discovery and optimization of novel protease-targeting therapeutics.
• Diagnostic Kits: Incorporated as a key component in diagnostic assays and kits designed to measure protease activity or inhibitor potency in clinical samples.
• Cell Biology Studies: Applied in cell culture and tissue experiments to modulate protease-mediated processes like signal transduction and apoptosis.
• Enzyme Purification: Utilized in affinity chromatography columns for the purification of specific serine proteases from complex mixtures.

Basic Information

Product Name	Trigramin
CAS No.	111019-84-2
Molecular Formula	C184H273N55O52S6
Molecular Weight	4171.9 g/mol
Synonyms	Trigramin (RGD-containing peptide); H-Gly-Gly-Gly-Gly-Gly-Arg-Gly-Asp-Ser-Pro-Cys-NH2 (Disulfide bridge: Cys10-Cys58); Arg-Gly-Asp (RGD) Peptide Inhibitor; Serine Protease Inhibitor Trigramin; Snake Venom-derived RGD Peptide; Platelet Aggregation Inhibitor Trigramin; GPIIb/IIIa Antagonist
EINECS	Contact for details

Quality Control

Our Trigramin is produced under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is characterized using advanced analytical techniques including HPLC, mass spectrometry, and amino acid analysis. We provide comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and bioactivity assay results to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under desiccant or inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity (IC50)	Specified per batch

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.