Description

Fmoc-D-Lys-Oh CAS NO 110990-08-4 is a high-purity, protected amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This compound is essential for the controlled, sequential assembly of peptides, enabling the incorporation of the D-isomer of lysine into custom sequences. It is a critical building block for researchers and manufacturers in pharmaceutical development, biotechnology, and academic research focused on creating novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated or manual synthesis of custom peptide sequences.
• Pharmaceutical Research & Development: For the creation of peptide drug candidates, including antimicrobial peptides (AMPs) and hormone analogs.
• Bioconjugation and Probe Development: Utilized to introduce a D-lysine residue with a free side-chain amine (after deprotection) for site-specific labeling with fluorophores, biotin, or other functional groups.
• Structural Biology Studies: Incorporation into peptides to study the effects of D-amino acids on peptide stability, conformation, and biological activity.
• Combinatorial Chemistry Libraries: Serves as a building block in the generation of diverse peptide libraries for high-throughput screening.
• Production of Peptide Fragments: For the synthesis of specific fragments used in epitope mapping or antibody production.

Basic Information

Item	Details
Product Name	Fmoc-D-Lys-Oh
CAS No.	110990-08-4
Molecular Formula	C21H24N2O4
Molecular Weight	368.43 g/mol
Synonyms	Fmoc-D-lysine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-lysine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-aminohexanoic acid; Fmoc-D-Lys-OH; Nα-Fmoc-D-lysine; Fmoc-D-Lysine-OH; D-Lysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our Fmoc-D-Lys-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity, ensuring it meets the exacting standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and performance. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.