Description

2,4-Difluorophenylbutyric Acid is a high-purity fluorinated aromatic carboxylic acid building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and novel materials, where the introduction of fluorine atoms is critical for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic molecules where fluorination enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key precursor in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms to improve pesticidal activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Used in the research and production of fluorinated organic compounds for electronic applications, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Organic Synthesis Building Block: Employed in various name reactions and coupling chemistries to introduce the 2,4-difluorophenyl moiety into more complex molecular architectures in academic and industrial R&D settings.
• Fluorine Chemistry Research: An important reagent for studying structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal and material chemistry.

Basic Information

Product Name	2,4-Difluorophenylbutyric Acid
CAS No.	110931-78-7
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	4-(2,4-Difluorophenyl)butanoic Acid; 2,4-Difluorobenzene butanoic Acid; 4-(2,4-Difluorophenyl)butyric Acid; Butanoic acid, 4-(2,4-difluorophenyl)-; γ-(2,4-Difluorophenyl)butyric Acid; 2,4-DFPBA; 110931-78-7 (CAS)
EINECS	Contact for details

Quality Control

Our 2,4-Difluorophenylbutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.