Description

Suc-Phe-Ala-Ala-Phe-Pna is a synthetic, chromogenic peptide substrate designed for enzymatic activity studies. This compound is a critical tool for researchers and manufacturers requiring precise measurement of protease and peptidase activity. It is primarily utilized in biochemical research, pharmaceutical development, and quality control within the biotechnology sector.

Application

• Protease/Peptidase Assays: As a chromogenic substrate for the kinetic study and quantification of enzyme activity, particularly for chymotrypsin-like proteases.
• Biochemical Research: Used in academic and industrial laboratories to investigate enzyme mechanisms, inhibition, and substrate specificity.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential therapeutic enzyme inhibitors.
• Diagnostic Reagent Development: Serves as a key component in the formulation of diagnostic kits for detecting specific enzymatic markers.
• Quality Control in Biomanufacturing: Used to monitor and validate the activity of enzyme batches during production processes.

Basic Information

Product Name	Suc-Phe-Ala-Ala-Phe-Pna
CAS No.	110906-89-3
Molecular Formula	C40H48N6O10
Molecular Weight	772.85 g/mol
Synonyms	N-Succinyl-L-phenylalanyl-L-alanyl-L-alanyl-L-phenylalanine p-nitroanilide; Suc-F-A-A-F-pNA; Suc-Phe-Ala-Ala-Phe-pNA; Substrate for Chymotrypsin; Chromogenic Substrate Suc-FAAF-pNA; N-Succinyl-Phe-Ala-Ala-Phe-pNA; Protease Substrate 110906-89-3
EINECS	Contact for details

Quality Control

Our Suc-Phe-Ala-Ala-Phe-Pna is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assays. We adhere to GMP principles for laboratory chemical production to support the integrity of your scientific work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may affect stability and performance. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Conforms to reference standard in chymotrypsin assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.