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n-Boc-Dl-4-Methylphenylalanine CAS NO 110762-12-4


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CAS No.:110762-12-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Boc-Dl-4-Methylphenylalanine is a protected amino acid derivative of significant importance in synthetic organic chemistry. This compound serves as a crucial chiral building block for the construction of complex peptides and peptidomimetics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents and bioactive molecules.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
  • Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for introducing the 4-methylphenylalanine residue with a tert-butoxycarbonyl (Boc) protecting group on the amine.
  • Proteomics Research: Employed in the design and study of modified peptides to investigate protein structure-function relationships.
  • Chemical Biology: Utilized for creating custom amino acid analogs to probe enzyme active sites or modulate biological activity.
  • Agrochemical Development: Acts as a building block for synthesizing novel compounds with potential pesticidal or herbicidal activity.
  • Material Science: Potential precursor for specialty polymers and advanced materials requiring specific amino acid functionalities.

Basic Information

Product Name n-Boc-Dl-4-Methylphenylalanine
CAS No. 110762-12-4
Molecular Formula C₁₅H₂₁NO₄
Molecular Weight 279.33 g/mol
Synonyms Boc-4-Me-Phe-OH; Boc-4-methyl-DL-phenylalanine; N-(tert-Butoxycarbonyl)-4-methyl-DL-phenylalanine; tert-Butyl (4-methylphenyl)alaninate; DL-4-Methylphenylalanine N-Boc derivative; N-Boc-4-methyl-DL-phenylalanine; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-(4-methylphenyl)propanoic acid
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Quality Control

Our n-Boc-Dl-4-Methylphenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) DL-mixture (Racemic)
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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