Description

n-Boc-n-Methyl-(S)-Homophenylalanine is a high-purity, chiral amino acid derivative featuring both tert-butoxycarbonyl (Boc) and N-methyl protective groups. This compound is a critical building block in modern pharmaceutical synthesis, enabling the development of complex, biologically active molecules with enhanced metabolic stability and bioavailability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of peptide-based therapeutics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce a modified phenylalanine residue with enhanced lipophilicity.
• API Development: Serves as a crucial building block in the research and production of Active Pharmaceutical Ingredients (APIs) targeting various disease pathways.
• Chemical Biology Research: Employed in the design and synthesis of peptide mimetics and molecular probes for studying protein-protein interactions.
• Process Chemistry: Utilized in process development and scale-up for the commercial manufacturing of complex organic molecules.

Basic Information

Product Name	n-Boc-n-Methyl-(S)-Homophenylalanine
CAS No.	110755-73-2
Molecular Formula	C₁₇H₂₅NO₄
Molecular Weight	307.38 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)(methyl)amino)-4-phenylbutanoic acid; Boc-N-Me-(S)-homoPhe-OH; (S)-N-Boc-N-methylhomophenylalanine; N-(tert-Butoxycarbonyl)-N-methyl-L-homophenylalanine; N-Boc-N-methyl-L-homophenylalanine; Boc-N-methyl-L-homophe; tert-Butyl (S)-(1-carboxy-3-phenylpropyl)(methyl)carbamate
EINECS	Contact for details

Quality Control

Our n-Boc-n-Methyl-(S)-Homophenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade pharmaceutical standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen or argon atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.