Description

Proto-Oncogene Protein C-Fes-Fps is a recombinant protein corresponding to the Fes/Fps tyrosine kinase, a key regulator in cellular signaling pathways. This high-purity reagent is essential for biochemical and pharmacological research focused on oncogenesis, cell differentiation, and immune response modulation. It is primarily utilized by researchers and developers in the fields of oncology, molecular biology, and drug discovery for kinase activity assays, inhibitor screening, and mechanistic studies.

Application

• Kinase Activity Assays: Used as a substrate or enzyme source in in vitro kinase assays to study phosphorylation mechanisms and signaling cascades.
• Drug Discovery & Screening: A critical target protein for high-throughput screening (HTS) of potential tyrosine kinase inhibitors for cancer therapy.
• Biochemical Research: Employed in studies investigating the role of Fes/Fps in hematopoietic cell differentiation, inflammation, and immune cell function.
• Antibody Validation: Serves as a positive control and standard for the development and validation of specific antibodies against the c-Fes protein.
• Signal Transduction Studies: Used to elucidate downstream effector pathways and protein-protein interactions mediated by Fes kinase activity.
• Diagnostic Development: Potential use as a calibrated antigen in the development of research-use-only (RUO) diagnostic assays.

Basic Information

Product Name	Proto-Oncogene Protein C-Fes-Fps
CAS No.	110736-90-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	FES Proto-Oncogene, Tyrosine Kinase; c-Fes; FPS; p92c-fes; p93c-fes; Feline Sarcoma Oncogene; Proto-Oncogene c-Fes; FES Tyrosine Kinase
EINECS	Contact for details

Quality Control

Our recombinant protein products are manufactured under stringent conditions to ensure high batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment, identity confirmation, and activity assays. A Certificate of Analysis (COA) detailing specific results for purity, endotoxin levels, and biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE/Western Blot)	Corresponds to c-Fes/Fps protein
Purity (SDS-PAGE)	> 90%
Protein Content	Determined by UV absorbance
Biological Activity	Confirmed by kinase activity assay
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.