Description

1-Butanone, 4-Chloro-2-Fluoro-1-(4-Fluorophenyl)- (9Ci) is a specialized fluorinated organic compound that serves as a valuable building block in advanced chemical synthesis. Its unique structure, featuring both chloro and fluoro substituents on an aromatic ketone backbone, makes it a critical intermediate for creating complex molecules with tailored properties. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where precise molecular architecture is paramount for developing new active ingredients.

Application

This fluorinated ketone intermediate is designed for high-value synthesis applications where structural precision is non-negotiable. Its primary uses include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the introduction of fluorine atoms enhances bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and facilitating challenging cross-coupling reactions.

Basic Information

Product Name	1-Butanone, 4-Chloro-2-Fluoro-1-(4-Fluorophenyl)- (9Ci)
CAS No.	110690-93-2
Molecular Formula	C10H9ClF2O
Molecular Weight	218.63 g/mol
Synonyms	4-Chloro-2-fluoro-1-(4-fluorophenyl)butan-1-one; 1-(4-Fluorophenyl)-4-chloro-2-fluorobutan-1-one; 4-Chloro-2-fluoro-4'-fluorobutyrophenone; 110690-93-2; Butan-1-one, 4-chloro-2-fluoro-1-(4-fluorophenyl)-; 4-Chloro-2-fluoro-1-(4-fluorophenyl)butanone
EINECS	Contact for details

Quality Control

Our production of 1-Butanone, 4-Chloro-2-Fluoro-1-(4-Fluorophenyl)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthesis workflows. All material is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with cGMP and ISO 9001 standards for advanced intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong bases and fluorides; ensure it is stored separately from such materials. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.