Description

n-Desmethyltimelotem is a key pharmaceutical intermediate and reference standard of significant importance in modern medicinal chemistry and analytical research. Its primary value lies in its role as a major metabolite and synthetic precursor for the development and quality control of active pharmaceutical ingredients (APIs). This compound is essential for research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in drug metabolism studies, impurity profiling, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of advanced active pharmaceutical ingredients (APIs) and related compounds.
• Reference Standard: Used as a certified standard for analytical method development, validation, and quality control (QC) in HPLC, LC-MS, and GC-MS.
• Metabolite Studies: Serves as a key metabolite reference in pharmacokinetic and drug metabolism research (DMPK).
• Impurity Profiling: Employed for the identification and quantification of process-related impurities and degradation products in pharmaceutical formulations.
• Chemical Research: Valuable building block in organic synthesis for creating novel molecular libraries and exploring structure-activity relationships (SAR).
• Regulatory Compliance: Supports regulatory filings by providing necessary impurity and degradation product standards for ICH guidelines.

Basic Information

Product Name	n-Desmethyltimelotem
CAS No.	110622-75-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Desmethyltimelotem; Timelotem Impurity; Timelotem Metabolite; Timelotem Related Compound; 110622-75-8; n-Desmethyl Timelotem; Desmethyl-timelotem
EINECS	Contact for details

Quality Control

Our n-Desmethyltimelotem is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical reference standards and intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.