Description

Bradykinin, Met-Ile-Ser- is a synthetic peptide fragment of the endogenous vasoactive peptide bradykinin. This compound is of significant value for biochemical and pharmacological research, serving as a critical tool for studying the kinin-kallikrein system, receptor binding, and inflammatory pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on cardiovascular, inflammatory, and pain research.

Application

• Biochemical Research: Used as a reference standard and substrate in enzymatic studies of kinin metabolism.
• Pharmacological Studies: Employed in receptor binding assays and functional studies to investigate bradykinin receptor (B1/B2) subtypes and signaling.
• Drug Discovery & Development: Serves as a key intermediate or analog in the design and screening of novel anti-inflammatory, analgesic, or cardiovascular therapeutic agents.
• Cell Biology: Applied in vitro to study cellular responses such as vasodilation, smooth muscle contraction, and pain signal transduction.
• Diagnostic Development: Utilized in the development and calibration of immunoassays (e.g., ELISA) for detecting bradykinin-related peptides.

Basic Information

Product Name	Bradykinin, Met-Ile-Ser-
CAS No.	110538-07-3
Molecular Formula	C20H34N6O6S
Molecular Weight	486.59 g/mol
Synonyms	Met-Ile-Ser-Bradykinin; Bradykinin (1-3); H-Met-Ile-Ser-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; BK (1-3); MIS-Bradykinin; Bradykinin fragment 1-3; L-Methionyl-L-isoleucyl-L-seryl-bradykinin
EINECS	Contact for details

Quality Control

Our Bradykinin, Met-Ile-Ser- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, water content, and peptide content are provided and available upon request to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.