Description

2,2,2-Trifluoro-n-5-Oxazolylacetamide is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl and oxazole moieties, enabling the construction of complex molecular architectures. This high-purity intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and process development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity, metabolic stability, and lipophilicity.
• Advanced Material Precursor: Serves as a building block for specialty polymers, liquid crystals, or organic electronic materials requiring specific fluorinated heterocyclic components.
• Chemical Biology & Proteomics: Employed as a tagged scaffold or a reactive handle in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in fluorine chemistry, heterocyclic chemistry, and new synthetic methodology development.

Basic Information

Item	Detail
Product Name	2,2,2-Trifluoro-n-5-Oxazolylacetamide
CAS No.	110281-31-7
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	2,2,2-Trifluoro-N-(1,3-oxazol-5-yl)acetamide; 5-(2,2,2-Trifluoroacetamido)oxazole; 2,2,2-Trifluoroacetamide, N-5-oxazolyl-; N-(Oxazol-5-yl)-2,2,2-trifluoroacetamide; 5-(Trifluoroacetylamino)oxazole; TFAA-Oxazole; 5-Aminoxazole trifluoroacetamide derivative
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-5-Oxazolylacetamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.