Description

D-Homoserine, n-[(1,1-Dimethylethoxy)Carbonyl]-, 1,1-Dimethylethyl Ester is a protected derivative of the non-proteinogenic amino acid homoserine, featuring tert-butoxycarbonyl (Boc) and tert-butyl ester protecting groups. This compound is a critical building block in advanced organic synthesis, particularly for the controlled construction of peptides and complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the homoserine moiety while protecting reactive side-chain functionalities.
• Chemical Biology Research: Serves as a precursor for synthesizing enzyme inhibitors, probes, and other tools to study biological pathways and protein function.
• Agrochemical Development: Employed in the synthesis of novel, complex molecules with potential herbicidal or pesticidal activity.
• Material Science: Can be utilized in the creation of specialized polymers and dendrimers with tailored properties for biomedical applications.
• Academic Research: A valuable reagent for methodological studies in organic chemistry, asymmetric synthesis, and protecting group strategies.

Basic Information

Product Name	D-Homoserine, n-[(1,1-Dimethylethoxy)Carbonyl]-, 1,1-Dimethyl Ester
CAS No.	110207-49-3
Molecular Formula	C13H25NO5
Molecular Weight	275.34 g/mol
Synonyms	Boc-D-Homoserine(OtBu)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-4-(tert-butoxy)-4-oxobutanoic acid; D-2-Amino-4-(tert-butoxy)-4-oxobutanoic acid N-Boc derivative; tert-Butyl (R)-2-((tert-butoxycarbonyl)amino)-4-(tert-butoxy)-4-oxobutanoate; Boc-Homoserine(OtBu)-D-OH; D-Homoserine(tBu) Boc; N-Boc-D-homoserine tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.