Description

Antistasin CAS NO 110119-38-5 is a potent, selective, and reversible inhibitor of the serine protease factor Xa, playing a critical role in the regulation of blood coagulation pathways. This high-purity compound is essential for advanced biochemical research and pharmaceutical development, particularly in the study of thrombosis and hemostasis. It is primarily utilized by researchers in life sciences, diagnostic kit manufacturers, and developers of novel anticoagulant therapies.

Application

• Biochemical Research: Used as a key reagent in enzymatic studies to investigate the coagulation cascade, specifically for inhibiting factor Xa activity in vitro.
• Pharmaceutical R&D: Serves as a reference standard and lead compound in the development of new direct oral anticoagulants (DOACs) and antithrombotic drugs.
• Diagnostic Assays: Employed as a critical component in the calibration and validation of clinical diagnostic kits for measuring blood clotting factors and anticoagulant efficacy.
• Cell Biology Studies: Applied in research to understand the role of factor Xa in cellular signaling, inflammation, and tissue repair processes.
• Quality Control: Acts as a purity standard for the manufacturing and quality assurance of related therapeutic proteins and peptides.

Basic Information

Product Name	Antistasin
CAS No.	110119-38-5
Molecular Formula	C84H118N22O26S4
Molecular Weight	1916.3 g/mol
Synonyms	Antistasin (Hirudinaria manillensis); FXa Inhibitor (Antistasin); Factor Xa Inhibitor (Antistasin); Anticoagulant Peptide Antistasin; Leech-derived Antistasin; Proteinase Inhibitor Antistasin; Antistasin I; Contact for details on additional aliases.
EINECS	Contact for details

Quality Control

Our Antistasin is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and biological activity assays to ensure potency and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Potency (Anti-Factor Xa Activity)	≥ 90% of labeled activity
Water Content (Karl Fischer)	≤ 5.0%
Endotoxin Level	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.