Description

12-Epi-Napelline is a diterpenoid alkaloid, a specific stereoisomer of napelline, known for its complex polycyclic structure. This high-purity reference standard is critical for analytical research, quality control, and pharmacological studies due to its precise chemical identity. It is primarily utilized by researchers and quality assurance professionals in the pharmaceutical, biotechnology, and academic sectors for method development, impurity profiling, and biological activity screening.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, assay, and purity testing of related alkaloids in raw materials and finished products.
• Biochemical Research: Serves as a key intermediate or target molecule in studies exploring the structure-activity relationships of diterpenoid alkaloids.
• Analytical Method Development: Employed in calibrating and validating analytical instruments such as HPLC, LC-MS, and NMR for precise quantification.
• Impurity Profiling: Essential for characterizing and controlling process-related impurities and degradation products in pharmaceutical manufacturing.
• Natural Product Isolation & Synthesis: Acts as a benchmark compound in the isolation, purification, and synthetic chemistry of complex natural products.

Basic Information

Product Name	12-Epi-Napelline
CAS No.	110064-71-6
Molecular Formula	C22H33NO3
Molecular Weight	359.51 g/mol
Synonyms	12-Epinapelline; (1α,14α,16β)-20-Ethyl-1,14,16-trimethoxy-4-(methoxymethyl)aconitane-7,8-diol; 12-epi-Napellin; 12-Epi-napelline (8CI); Aconitane-7,8-diol, 20-ethyl-1,14,16-trimethoxy-4-(methoxymethyl)-, (1α,14α,16β)-
EINECS	Contact for details

Quality Control

Our 12-Epi-Napelline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and reference materials. A detailed Certificate of Analysis (COA) specifying batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.