Description

3-Bromo-1-Ethylpyrrolidin-2-One is a versatile brominated pyrrolidinone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive bromine substituent and lactam functionality, enabling precise molecular construction for complex target molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the pyrrolidinone core contributes to biological activity.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers and advanced materials.
• Ligand and Catalyst Development: Useful for constructing complex nitrogen-containing ligands for asymmetric catalysis and metal-organic frameworks.

Basic Information

Product Name	3-Bromo-1-Ethylpyrrolidin-2-One
CAS No.	110027-12-8
Molecular Formula	C6H10BrNO
Molecular Weight	192.06 g/mol
Synonyms	1-Ethyl-3-bromopyrrolidin-2-one; 3-Bromo-1-ethyl-2-pyrrolidinone; 2-Pyrrolidinone, 3-bromo-1-ethyl-; 3-Bromo-1-ethylpyrrolidinone; 3-Bromopyrrolidin-2-one, 1-ethyl-; N-Ethyl-3-bromo-2-pyrrolidinone
EINECS	Contact for details

Quality Control

Our 3-Bromo-1-Ethylpyrrolidin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.