Description

Lhrh, n-Ac-3(2-Naphthyl)Ala(1)-Phe(2,3)-Arg(6)-Phe(7)-Alanh2(10)- CAS NO 110014-25-0 is a synthetic peptide analog, specifically a modified decapeptide derivative of the native Luteinizing Hormone-Releasing Hormone (LHRH). This compound matters for its role as a key research-grade biochemical tool in endocrinology and pharmaceutical development, enabling the study of hormone receptor interactions and signaling pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on peptide-based therapeutics and diagnostic applications.

Application

• Biochemical Research: Used as a reference standard and active probe in studies of the LHRH receptor (GnRH receptor) function and signaling mechanisms.
• Pharmaceutical Development: Serves as a critical intermediate or lead compound in the discovery and development of novel peptide-based therapeutics targeting hormonal disorders.
• Endocrinology Studies: Applied in in vitro and in vivo models to investigate the hypothalamic-pituitary-gonadal axis and related physiological processes.
• Analytical Standard: Employed as a high-purity calibrant in analytical methods such as HPLC and mass spectrometry for peptide quantification and identification.
• Structure-Activity Relationship (SAR) Studies: The specific naphthylalanine modification makes it valuable for investigating the impact of aromatic side chains on receptor binding affinity and biological activity.

Basic Information

Item	Details
Product Name	Lhrh, n-Ac-3(2-Naphthyl)Ala(1)-Phe(2,3)-Arg(6)-Phe(7)-Alanh2(10)- CAS NO 110014-25-0
CAS No.	110014-25-0
Molecular Formula	C70H92N18O13
Molecular Weight	1369.6 g/mol
Synonyms	Ac-3-(2-Naphthyl)-D-Ala1-D-Phe2-D-Trp3-D-Arg6-D-Phe7-LHRH; [Ac-D-3-(2-Naphthyl)Ala1, D-Phe2, D-Trp3, D-Arg6, D-Phe7]-LHRH; Modified LHRH Antagonist Analog; GnRH Antagonist Peptide Derivative; Luteinizing Hormone-Releasing Hormone Analog; Decapeptide LHRH Derivative; Research Peptide 110014-25-0
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Every batch is characterized using advanced analytical techniques including HPLC, MS, and NMR to confirm identity and purity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. We adhere to a quality management system to guarantee batch-to-batch consistency and traceability for our research and development customers.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular formula
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.