Description

4,5,5-Trifluoropent-4-enoic Acid is a high-value fluorinated building block characterized by its reactive carboxylic acid and alkene functionalities. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where the introduction of fluorine atoms is critical for modulating biological activity, stability, and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and biological efficacy.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers used in electronic display technologies to improve performance and stability.
• Polymer Modification: Incorporated as a functional monomer to create specialty fluoropolymers with unique surface properties and chemical resistance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, Michael additions, and other transformations to construct complex fluorinated molecular architectures.

Basic Information

Product Name	4,5,5-Trifluoropent-4-enoic Acid
CAS No.	110003-22-0
Molecular Formula	C5H5F3O2
Molecular Weight	154.09 g/mol
Synonyms	4,5,5-Trifluoropent-4-enoic Acid; 4-Pentenoic acid, 4,5,5-trifluoro-; 110003-22-0; 4,5,5-Trifluoro-4-pentenoic acid; Trifluoropentenoic acid; 4,5,5-Trifluoropent-4-en-1-oic acid; 4,5,5-Trifluoro-4-penten-1-oic acid; 4,5,5-Trifluoropent-4-enoic acid
EINECS	Contact for details

Quality Control

Our 4,5,5-Trifluoropent-4-enoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.