Description

Bezafibroyl-Coenzyme A is a critical biochemical intermediate, specifically the activated Coenzyme A thioester derivative of bezafibrate. This compound is essential for research into lipid metabolism and peroxisome proliferator-activated receptor (PPAR) signaling pathways. It serves as a vital tool for scientists and pharmaceutical developers in the fields of metabolic disease research, drug discovery, and enzymology. The high-purity material is designed to meet the stringent requirements of advanced biochemical assays and mechanistic studies.

Application

• Biochemical Research: Used as a substrate or reference standard in enzymatic studies related to fatty acid activation and metabolism.
• Drug Discovery & Development: A key intermediate for investigating the mechanism of action of fibrate drugs and developing novel PPAR agonists.
• Metabolic Pathway Analysis: Employed in in vitro assays to study lipid biosynthesis, β-oxidation, and related metabolic disorders.
• Enzyme Kinetics: Serves as a specific substrate for characterizing acyl-CoA synthetases and other relevant enzymes.
• Pharmaceutical Reference Standard: Utilized for quality control and analytical method development in pharmaceutical R&D.
• Academic Research: Supports fundamental research in biochemistry, molecular biology, and pharmacology at universities and research institutes.

Basic Information

Product Name	Bezafibroyl-Coenzyme A
CAS No.	109881-30-3
Molecular Formula	C38H62N7O19P3S
Molecular Weight	1057.91 g/mol
Synonyms	Bezafibrate-CoA; Bezafibroyl-Coenzyme A; Bezafibrate Coenzyme A Conjugate; CoA-Bezafibrate; Bezafibroyl-CoA; 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoyl-CoA; PPAR Activator-CoA Derivative
EINECS	Contact for details

Quality Control

Our Bezafibroyl-Coenzyme A is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results for purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.