Description

2H-Imidazol-2-One, 1,3-Dihydro-4-Methyl-5-(Trifluoroacetyl)- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoroacetyl-substituted imidazolone structure, which is a key precursor for developing novel pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic materials with specific electronic or optical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2H-Imidazol-2-One, 1,3-Dihydro-4-Methyl-5-(Trifluoroacetyl)- (9Ci)
CAS No.	109777-66-4
Molecular Formula	C6H5F3N2O2
Molecular Weight	194.11 g/mol
Synonyms	4-Methyl-5-(trifluoroacetyl)imidazolidin-2-one; 1,3-Dihydro-4-methyl-5-(trifluoroacetyl)-2H-imidazol-2-one; 5-(Trifluoroacetyl)-4-methyl-2-imidazolidinone; 4-Methyl-5-trifluoroacetyl-2-imidazolidinone; Methyl-trifluoroacetyl-imidazolidinone; TFAMI
EINECS	Contact for details

Quality Control

Our 2H-Imidazol-2-One, 1,3-Dihydro-4-Methyl-5-(Trifluoroacetyl)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.