Description

Prolyl-Psi(Methylamino)Leucyl-Glycinamide is a synthetic peptide compound with the CAS Registry Number 109772-54-5. This specialized molecule is of significant interest in advanced biochemical research and pharmaceutical development due to its unique structural modifications. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, peptide synthesis, and metabolic studies, addressing the need for high-purity, well-characterized building blocks.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel therapeutic peptides and peptidomimetics targeting various disease pathways.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to optimize drug candidate properties like bioavailability and receptor binding affinity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate protease activity and peptide metabolism.
• Reference Standard: Employed as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control and method validation in peptide manufacturing.
• Academic Research: A valuable tool for universities and research institutes studying peptide conformation, stability, and novel synthetic methodologies.

Basic Information

Product Name	Prolyl-Psi(Methylamino)Leucyl-Glycinamide
CAS No.	109772-54-5
Molecular Formula	C19H34N6O4
Molecular Weight	410.51 g/mol
Synonyms	Pro-ψ[CH2NH]-Leu-Gly-NH2; Psi(Methylamino) Pseudopeptide; (S)-2-Pyrrolidinecarboxylic acid, 1-[(2S)-2-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]methylamino]-1-oxo-3-(aminocarbonyl)propyl]-; Prolyl-Pseudoiso(Methylamino)Leucyl-Glycinamide; Pro-ψ[CH2-NH]-Leu-Gly-NH2; Peptide Inhibitor Intermediate; Methylamino Pseudopeptide Derivative; 109772-54-5
EINECS	Contact for details

Quality Control

Our Prolyl-Psi(Methylamino)Leucyl-Glycinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.