Description

3-Iodo-5,5,6,6,7,7,8,8,8-Nonafluorooctan-1-Ol is a high-value, multi-functional fluorinated building block characterized by its unique combination of a terminal alcohol group and a perfluorinated alkyl chain terminated with an iodine atom. This molecular architecture is critical for introducing lipophilicity, chemical stability, and specific reactivity into advanced materials and pharmaceuticals. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for synthesizing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and CNS therapeutics, where the fluorinated chain enhances metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in creating advanced, environmentally persistent active ingredients for herbicides and pesticides, leveraging the stability of the perfluorinated segment.
• Fluorinated Surfactant & Polymer Precursor: Serves as a monomer or modifier for producing specialty polymers, coatings, and surfactants with exceptional oil, water, and stain repellency.
• Material Science Research: Employed in developing novel liquid crystals, electrolytes for batteries, and surface-modifying agents due to its unique physicochemical properties.
• Radiolabeling & Imaging Agent Development: The iodine atom provides a potential site for radioiodination, making it useful in preclinical research for PET imaging or targeted radiotherapy probes.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing long, fluorinated chains into molecules via substitution or coupling reactions, enabling precise property modulation.

Basic Information

Product Name	3-Iodo-5,5,6,6,7,7,8,8,8-Nonafluorooctan-1-Ol
CAS No.	109574-81-4
Molecular Formula	C8H4F9IO
Molecular Weight	438.01 g/mol
Synonyms	1H,1H,2H,2H-Perfluorooctyl Iodide, 3-Iodo Derivative; 3-Iodo-1H,1H,2H,2H-perfluorooctan-1-ol; 1H,1H,2H,2H-Perfluorooctyl Iodohydrin; 2-(Perfluorohexyl)ethyl Iodide Alcohol; 3-Iodo-5,5,6,6,7,7,8,8,8-nonafluorooctanol; 8-Iodo-1,1,2,2,3,3,4,4,4-nonafluorobutyl Alcohol (rearranged numbering); F6H2I-OH (abbreviation); 1-Iodo-3-(perfluorohexyl)propan-1-ol
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-5,5,6,6,7,7,8,8,8-Nonafluorooctan-1-Ol is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including NMR (¹H, ¹⁹F), GC/HPLC, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to the light-sensitive and reactive iodine moiety, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 0.5%
¹H NMR / ¹⁹F NMR	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.