Description

1-(Prop-2-Enoyl)Piperidine-4-Carboxylic Acid is a high-purity, functionalized piperidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and an acrylamide-like moiety, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Organic Synthesis Building Block: Used in amide coupling reactions, Michael additions, and polymerizations to introduce functionalized piperidine scaffolds.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides with tailored biological activity.
• Material Science: Potential monomer or cross-linker for creating specialty polymers with specific thermal or mechanical properties.
• Chemical Biology & Proteomics: Can be used to develop activity-based probes or affinity tags for studying protein function.

Basic Information

Product Name	1-(Prop-2-Enoyl)Piperidine-4-Carboxylic Acid
CAS No.	109486-01-3
Molecular Formula	C9H13NO3
Molecular Weight	183.21 g/mol
Synonyms	1-Acryloylpiperidine-4-carboxylic acid; 4-Carboxy-1-acryloylpiperidine; 1-(Acryloyl)piperidine-4-carboxylic acid; Piperidine-4-carboxylic acid, 1-(1-oxo-2-propen-1-yl)-; 1-(Prop-2-en-1-one)piperidine-4-carboxylic acid; N-Acryloylisonipecotic acid
EINECS	Contact for details

Quality Control

Our 1-(Prop-2-Enoyl)Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.